Sentinels of the Multiverse is a cooperative card game published by Greater Than Games and released at Gen Con 2011. Players control a team of comic book-style heroes battling a villain. Each player controls one or more heroes, while a villain and environment deck each run themselves. A given game includes 3 to 5 heroes, 1 villain and 1 environment, which can be mixed and matched to create a number of different scenarios. The core game comes with 10 heroes, 4 villains, and 4 environments.
Hero decks include (usually) one card that represents the hero. It gives the hero's initial hit points and a power they may use. If the hero loses all of their hit points, the hero card is flipped over and the hero cannot play any cards or use any powers, but instead has three incapacitated abilities that can be used for the hero to continue to help their allies. Hero decks also contain forty other cards representing ongoing abilities, equipment, and one-shots that can be played. The heros lose the game when all of them are incapacitated.
Villain decks also include (usually) one card representing the villain. This card includes their starting hit points, rules for setting up the villain at the start of the game, abilities they take each turn, and a mechanism by which the card may be flipped over. The flipped version of the villain card represents another phase of the fight. Each villain has different flip mechanics. Villain decks also contain twenty-five other cards with one-shots, ongoings, minions, devices, and other types of cards that might be put into play. Villains are generally defeated when reduced to zero or fewer hit points, but may also have other win and/or lose conditions.
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