Not much is known about the past of Cain Marko on Earth-1815. Likely, his powers derived from the Crimson Gem of Cyttorak like on countless other realities. When the governments of this world enacted Operation: Zero Tolerance, a program to eliminate or incarcerate all super-humans, Cain found himself captured and placed in a maximum security prison where he spent months restrained in a device that prevented him from moving. During his incarceration Cain witnessed atrocities, including the death of mutant children, at the hands of his jailers.
Eventually, Cain's step-brother Charles Xavier was freed from incarceration by the reality hopping Exiles who were then on their first mission. The Exiles were under orders to find this realities greatest leader and were under the mistaken impression that Xavier was the man they sought. Xavier, having grown to hate humanity due to his own inhumane treatment knocked out the Exiles and sought out an army to wage genocide against normal humans. He freed Cain, who joined Xavier and other like-minded super-humans in the terrorist X-Men. Their first target was the New York Stock Exchange, where they were opposed by the Exiles who attempted to convince them that there was a better way than slaughtering humans. Cain wasn't able to subscribe to this way of thinking and in a clash with the Exiles powerhouse Thunderbird he was knocked out cold. Xavier and the rest of the X-Men were defeated shortly after.[1] Cain's fate remains unrevealed.
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